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Interviews were transcribed and coded in Atlas.ti. Following the selfdirected portion, qualitative interviews explored participants’ intuitive understanding of scoring direction.

For each graph, participants reported whether they thought the line represented a score that was getting ‘better,’ ‘worse,’ or ‘not sure.’ They were then shown various formats for presenting PRO data (e.g., line graphs, bar charts, heat maps). No instructions regarding the meaning of direction were provided. Participants first self-completed a sample PRO questionnaire and were then shown two line graphs: one labeled ‘general well-being’ with the line trending up and one labeled ‘shortness of breath’ with the line trending down. Patients were purposively sampled by cancer type, care setting, and education clinicians were purposively sampled by specialty and practice setting. METHODS: This mixed-methods study recruited cancer patients who had completed acute treatment and cancer clinicians from a network of academic and community practices. This study explored how patients and clinicians intuitively interpret increasing and decreasing PRO scores, with the goal of improving approaches for presenting PROs to promote understanding and use. Preliminary research suggests that this lack of consistency is confusing to patients and clinicians, creating a barrier to their use of PROs in practice. Smith, PhD, Johns Hopkins Bloomberg School of Public Health Elissa Bantug, MHS, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Emily Little, MPH, Johns Hopkins School of Medicine Michael Brundage, MD, Queen’s University, Kingston, ON, Canada PRO Data Presentation Stakeholder Advisory Board, Various Institutions AIMS: Whether higher scores represent better or worse outcomes varies across patient-reported outcome (PRO) measures and, in some cases, depends on the domain within a measure. Qual Life Res (2014) 23:1–184 DOI 10.1007/s1113-6 ABSTRACTS 21st Annual Conference of the International Society for Quality of Life Research  Springer International Publishing Switzerland 2014 Cutting Edge Research Plenary (1) What’s ‘‘Up’’: Patients’ and clinicians’ intuitive interpretation of PRO scores Claire Snyder, PhD, Johns Hopkins, Baltimore, MD, United States Katherine C.